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Forskning och personal

Forskning och personal

Forskargrupper

 

Structural Bioinformatics Laboratory (SBL)

Professor Mark S. Johnson

My research team at the  Structural Bioinformatics Laboratory (SBL) focuses on how biological molecules function to produce their biological consequences. Our team has broad expertise and hence applies multiple approaches to investigate different problems, primarily involving human proteins. Key approaches employed by us in our research are experimental structural biology (X-ray crystallography), structural bioinformatics (structure and molecular complex modeling), in silico screening for ligands and development of biologics, development and application of novel computational tools. Our research is made in close cooperation with research groups investigating the biological problem primarily using wet-lab experimental approaches. Our main current problems focus on transcription factors in very early human development; kinases and their involvement in disease processes; integrins – evolution and roles in disease  processes; engineering of enzymes for specific chemistries.

FD Tomi Airenne 
PhD Konstantin Denessiouk
PhD Alexandre Denesyuk 
FD Jukka Lehtonen Biocenter Finland Scientific IT Support

Professor Tiina A. Salminen

My research team at the Structural Bioinformatics Laboratory (SBL) focuses on 3D structures of proteins and, particularly, utilizing 3D structures to predict and understand protein function. We are interested in finding out how proteins interact with other molecules and what is the structural basis for their ligand specificity. Some of the proteins we are working with are important in human health and disease, are used as biocatalysts to produce drug molecules or in diagnostics of disease while others are of plant origin and important in maintaining the photosynthetic reaction, which is vital for all of us.

FD Jenny Isaksson
FD Serhii Vakal

 

Lipid Transfer Protein Research Group

Akademilektor Peter Mattjus

Our research is focused on lipid transfer proteins, in particular proteins specific for glycosphingolipids, such as the glycolipid transfer protein, GLTP, and the Phosphatidylinositol-four-phosphate adapter protein 2, FAPP2. We are also working on the relationship between glycosphingolipid transfer and synthesis, and the connection to the ceramide synthase family, CerS.

FD Max Lönnfors
MSc Josefin Halin

 

Ecophysiology of cyanotoxin production and cyanobacteria in terrestrial bioengineering

Docent Jussi Meriluoto

Zorica Svirčev, Prof. University of Novi Sad, Docent Åbo Akademi University
Sultana Akter, Researcher at University of Turku/Biotechnology
Tamara Dulić, PhD student

Aquatic cyanobacteria produce potent cyanotoxins with adverse health effects on humans and animals exposed e.g. via drinking water, aquaculture and recreation. We are currently comparing the secondary metabolite profiles and ecophysiological properties of aquatic and terrestrial cyanobacteria to identify biological and ecological functions of cyanotoxins.
Cyanobacteria are natural colonizers in hostile terrestrial environments often characterized by nutrient deficiency, high UV irradiation, toxic elements and limited water availability. Utilizing our BLOCDUST and Synergosis concepts we aim to establish novel cyanobacterial technology for the safe restoration of degraded and polluted areas affected by climate change and anthropogenic influence.

 

Roos-Mattjus lab

Akademilektor Pia Roos-Mattjus

My research group studies the family of heat shock transcription factors HSFs and their biological functions both during development, disease and during stressful conditions.

 

Doktorander

Ida Alanko (SBL)
Anders Backman (Lipid Transfer Protein Research Group)
Tamara Dulic (Detection Methods for Cyanobacterial Peptide Toxins)
Henrik Nurmi (Lipid Transfer Protein Research Group)
Vipin Ranga (SBL)
Marion Alix (SBL)
Mikael Ilomäki (SBL)

Gäst- och post doc forskare

Serhii Vakal
Ábris Bendes
Christine Touma
Juan Palacios Ortega
Mia Åstrand (SBL)
Vladimir Vukic (SBL)
Zorica Svircev

Epost: förnamn.efternamn@abo.fi

Uppdaterad 8.11.2021