Professor Mark S. Johnson
My research team at the Structural Bioinformatics Laboratory (SBL) focuses on how biological molecules function to produce their biological consequences. Our team has broad expertise and hence applies multiple approaches to investigate different problems, primarily involving human proteins. Key approaches employed by us in our research are experimental structural biology (X-ray crystallography), structural bioinformatics (structure and molecular complex modeling), in silico screening for ligands and development of biologics, development and application of novel computational tools. Our research is made in close cooperation with research groups investigating the biological problem primarily using wet-lab experimental approaches. Our main current problems focus on transcription factors in very early human development; kinases and their involvement in disease processes; integrins – evolution and roles in disease processes; engineering of enzymes for specific chemistries.
Senior Lecturer Tiina A. Salminen
My research team at the Structural Bioinformatics Laboratory (SBL) focuses on 3D structures of proteins and, particularly, utilizing 3D structures to predict and understand protein function. We are interested in finding out how proteins interact with other molecules and what is the structural basis for their ligand specificity. Some of the proteins we are working with are important in human health and disease, are used as biocatalysts to produce drug molecules or in diagnostics of disease while others are of plant origin and important in maintaining the photosynthetic reaction, which is vital for all of us.
PhD Jenny Isaksson
PhD Serhii Vakal
Senior Lecturer Peter Mattjus
Our research is focused on lipid transfer proteins, in particular proteins specific for glycosphingolipids, such as the glycolipid transfer protein, GLTP, and the Phosphatidylinositol-four-phosphate adapter protein 2, FAPP2. We are also working on the relationship between glycosphingolipid transfer and synthesis, and the connection to the ceramide synthase family, CerS.
Detection Methods for Cyanobacterial Peptide Toxins
Docent Jussi Meriluoto
PhD Lisa Spoof
PhD Kerstin Häggqvist
PhD Elina Palonen (Detection Methods for Cyanobacterial Peptide Toxins)
Senior Lecturer Pia Roos-Mattjus
My research group studies the family of heat shock transcription factors HSFs and their biological functions both during development, disease and during stressful conditions.
Ida Alanko (SBL)
Anders Backman (Lipid Transfer Protein Research Group)
Tamara Dulic (Detection Methods for Cyanobacterial Peptide Toxins)
Anna Möuts (Lipid and Membrane Biochemistry)
Henrik Nurmi (Lipid Transfer Protein Research Group)
Juan Palacios Ortega (Lipid and Membrane Biochemistry)
Vipin Ranga (SBL)
Mahlet Tamirat (SBL)
Mia Åstrand (SBL)
Vladimir Vukic (SBL)