Researchers at the division of cell biology investigate many of the most central functions of cells, such as signaling within and between cells, cell division and death, stress responses and inflammation. This basic research is tightly linked to understanding many human diseases such as cancer, muscle diseases, inflammatory diseases and diabetes.
The main research focus areas at Cell Biology at Åbo Akademi University are cell stress, survival and cell death, cellular decision-making processes, regulation of gene expression, the role of the cytoskeleton in normal and pathological processes, the relationship between inflammatory processes and tissue damage, tissue regeneration and degeneration. This basic research is tightly linked to understanding many human diseases such as cancer, muscle diseases, inflammatory diseases and diabetes. We use advanced methods to visualize cells and tissues, and the bioimaging possibilities at Åbo Akademi University are world-class. Cell Biology is also part of the Åbo Akademi University research profil in drug development and diagnostics, which is a joint focus area for the universities in Turku.
The Åbo Akademi University life sciences laboratories are active on the Kupittaa campus together with the life sciences and medical researchers from University of Turku and Turku University Hospital. Research in life sciences at Åbo Akademi University is supported by strong organizations such as BioCity Turku and Health Campus Turku, which strengthen the opportunities for collaboration and innovation on our campus. We also have access to advanced state of the art infrastructure through Turku Bioscience, Turku BioImaging and EuroBioimaging.
The ÅAU Center of Excellence project CellMech (Center of Excellence in Cellular Mechanostasis) is led by Cecilia Sahlgren, Professor in Cell Biology. CellMech studies how mechanical stress that generates from alterations in the blood flow or tissue stiffness (” tissue fibrosis”) effects the functions of cells and tissues. The research within CellMech is specifically focused on obtaining a deeper knowledge of how cells respond to mechanical stress at a molecular level, and, how the cellular mechanisms is regulated by mechanical stimuli. Through the studies, our researchers aim to profoundly contribute to the knowledge in the field of mechanomedicine regarding stimulation of tissue repair and therapies for diseases such as chronic wounds, cardiovascular diseases, and, chronic inflammation that can, if left untreated, cause cancer.
Research groups and researchers
The Cell Fate Lab
Professor Cecilia Sahlgren
The Cell Stress Lab
Professor Lea Sistonen
The Cytoskeletal and survival signaling Lab
Professor John Eriksson
The Epithelial Biology Lab
Associate Professor Diana Toivola
The Inflammatory Signalling Lab
Senior lecturer, docent Annika Meinander
The Molecular Immunology Lab
Lecturer Christer Lindqvist