ÅAFPC – Characterization Techniques

Surface Characterization

• Transmission and epi-fluorescence microscope with optical and video cameras  |  Nikon Microphot FXA
• Upright microscope with Nikon DS-FI2 camera   |  Olympus BX60 + BX-FLA
• Stereo microscope  |   Olympus SZX12
• Atomic Force Microscope (AFM)  |   Bruker MultiMode 8 AFM
• Atomic Force Microscope (AFM)   |   Ntegra-Prima AFM

Particle and Dispersion Characterization

• Particle size and zeta potential meter   |   Malvern Zetasizer Nano ZS
• Particle size and zeta potential meter   |   Malvern Zetasizer 3000
• Rheometers / DMA   |   Anton Paar MCR 702 & MCR 102e
• Capillary viscometer   |    ACA Systems AX-100
• Gas sorptometer    |    ASAP 2010 & |    Autosorb 1
• X-ray diffraction/scattering (XRD / SAXS)   |    Bruker D8 Discover

Solution and Liquid Crystal Characterization

• Tensiometer for liquids   |   Sensadyne 9000 Bubble Tensiometer
• KRÜSS Force Tensiometer 100
• Optical tension and contact angle meter (x 2)   |    KSV CAM 200
• Densitometer, vibrating tube  |   Anton-Paar DSA5000
• Tension and contact angle meter, receding & advancing  |    KSV Sigma 70
• Stability of emulsions, suspensions and foams   |    Formulaction Turbiscan Classic MA 2000
• Freezing point osmometer   |   Gonotec Osmomat 030)
• Membrane filtration and separation, 6 cells   |   Sterlitech cross-flow filtration equipment
• Membrane filtration and separation, 1 cell  |   Portalux Flat

Spectrometry

• FTIR Spectrometer   |   Perkin-Elmer FTIR-1000
• FTIR Spectrometer   |   Bruker, IFS 66S
• Luminescence Spectrometer  |  PerkinElmer LS50B
• UV-vis Spectrometer   |   Shimadzu UV-2501PC
• UV-vis-NIR Spectrometer, Integrating Sphere, Fibres, etc.  |   Perkin-Elmer Lambda 900 system
• UV-Vis Spectrometer   |   Thermo Scientific, NanoDrop 2000
• UV-Vis Spectrometer   |   PerkinElmer, Lambda 25
• Raman Spectrometer  |   Renishaw, Ramascope (system 1000)
• FTIR Microscope   |   Bruker IR Microscope A 590
• Raman microscope   |   Bruker R 590 Raman microscope

Other instruments

• Thermobalance with MS analysator   |   STA 449F1 Jupiter (TG) and QMS 403C Aêolos (MS)
• Quarz crystal microbalance   |   KSV QCM Z- 500
• CO2 incubator   |   Heracell 150i
• Ultra centrifuge 10-21000 rpm   |   Hermle Z36HK
• Potentiostat + multiconnection unit    |    PalmSense 4 + MUX-8
• Potentiostat + multiconnection unit    |    Ivium + HiMux.XR
• Microwave synthesis system   |   Discover SP
• Inductively Coupled Plasma Optical Emission Spectrometer (ICP-OES) | Perkin Elmer, Optima 5300 DV
• Ion chromatograph (IC) with Spark autosampler | Metrohm, 881 Compact IC pro
• Karl Fisher titrator | Metrohm, 860 KF Thermoprep
• Microwave (acid dissolution) oven | Anton Paar, Multiwave 3000
• Mercury porosimetry | Pascal 140/ 440, Thermo Electron S.p.A.

Cell Imaging

More information: Turku Bioscience/ Cell Imaging and Cytometry

• Widefield microscope   |   Zeiss Axiovert 200M (inverted microscope)
• Widefield microscope   |   Zeiss SteREO Lumar V12 with Microinjection
• Widefield microscope   |   EVOSfl cell culture microscope
• Widefield microscope   |   Leica DMRE (upright microscope)
• Widefield microscope   |   Leica DM RXA (upright microscope)
• Widefield microscope   |   Leica DM IRBE (inverted microscope)
• Confocal microscope   |   Zeiss LSM780
• Confocal microscope   |   3i CSU-W1 spinning disk
• Confocal microscope   |   Zeiss LSM510 with JPK Nanowizard II AFM
• Confocal microscope   |   Leica TCS SP5 Matrix
• Confocal microscope   |   Leica TCS SP1
• Confocal microscope   |   Leica TCS SP5 Multiphoton
• Confocal microscope   |   BD Pathway 855
• Confocal microscope   |   3i CSU22 spinning disk
• Fluorescence lifetime imaging microscopy FLIM   |    Lambert LIFA FLIM
• Total Internal Reflection Microscopy TIRFM   |    Zeiss TIRF microscope
• Fluorescence stereo microscope   |    Zeiss SteREO Lumar V12
• Laser-capture microsdissection LCM   |    Zeiss P.A.L.M. LCM
• Atomic Force Microscope   |    Agilent 5500 AFM
• Imaging    |    Perkin Elmer Operetta High Content Imaging System
• Flow cytometer    |    BD LSR Fortessa
• Flow cytometer    |    BD FACSCalibur
• Flow cytometer    |    BD LSR II
• Flow cytometer    |    BD Accuri C6
• Flow cytometer    |    BD FACSAria IIu
• Gel analyser   |    BioRad ChemiDoc MP
• Microplate reader   |    BioTek Synergy H1 multi-mode reader
• Gel analyser   |    Li-Cor Odyssey

Pharmacy

• Particle size analyses for liquid suspensions and dry powders   |   Sympatec GmbH / HelosKF
• UV-Vis Spectrophotometer   |   Thermo Scientific NanoDrop 2000c
• UV-Vis Spectrophotometer   |    PerkinElmer LAMBDA 35
• UV-Vis Spectrophotometer   |    VWR UV-6300PC Double Beam Spectrophotometer
• Fluorospectrometer   |    Thermo Scientific NanoDrop 3300
• Small scale microwave synthesis of nanoparticles    |    Anton Paar Monowave 300
• Dissolution testing of pharmaceutics   |    Sotax AT7 dissolution unit
• Fluorescence plate reader   |    Thermo Scientific Varioskan Flash
• Powder flow studies    |    FlowPro
• Compound structure analysis    |    PerkinElmer ATR-IR
• Surface structure analysis (custom built)    |    Scanning White Light Interferometer SWLI
• Disintegration studies of solid pharmaceutics    |    Sotax DT2
• Tapped density measurements of powder systems    |    Copley Scientific JV2000
• Melt flow measurements of casted films    |     Custom Scientific Instruments Melt flow indexer Type MF12
• Sample separation; nanoparticles    |    HealForce Neofuge 13
• Texture analyser of different materials    |    Stable Micro Systems TA.xt.plus Texture Analyser
• Thermal studies of active pharmaceutical ingredients and formulaitons   |    TA Instruments DSC Q2000 + Refridger Cooling System 40
• Microscopy    |    Westburg Evos XL
• Microscopy    |    Spektrometer AvaSpec-NIR512-1.7-EVO
• Osmometer   |    Knauer K-7400S Semi-Micro Osmometer
• Rheometer    |    Haake Mars 40

Organic Electronics

• Glove box   |    MBRAUN Unilab glove box
• Glove box   |    Vigor
• Laminar flow cabinets(multiple)   |   Koiair KR-100
• E-beam evaporator    |    Moorfield Minilab 090
• Vacuum evaporator    |    CVC
• Vacuum evaporator    |    JEOL JEE-4B
• Thickness meter    |    Intellemetrics IL 150
• Thickness meter    |    Maxtek TM-100
• Vacuum drying oven < 250 ºC   |    Binder
• Sputter, O+2 and N+2 plasma etcher    |    Bal-Tec SCD 050
• Langmuir-Blodgett film deposition equipment   |   KSV 2200
• Atomic force microscope    |    Veeco diCaliber AFM
• Upright microscope    |    Olympus BX60 with fluorescence equipment and CCD-camera
• Modular DC Source/Monitor    |    Agilent 4142B
• Parameter analysator    |     Keithley 4200-SCS
• Voltage source    |    Keithley 230
• Current source    |    Keithley 220
• Power source (multiple)    |     Kikusui, Agilent E3631A, Keithley 2230-30-1, …
• Signal/waveform generators (multiple)    |    Stanford DS345, DG535, Agilent 33522B, …
• Electrometer   |    Keithley 617
• Sourcemeters (multiple)    |    Keithley 2612, 2636, 2400
• Picoammeter    |     Keithley 485
• Multimeters (multiple)   |     Keithley 2000, 2001, 2100 (2x), Agilent 34410A, 34461A, …
• Lock-in amplifiers (multiple)    |     Stanford SR510, SR830
• Memory oscilloscopes (multiple)   |    Tektronix 680B, 2230, Agilent MSOX2002, …
• Oscilloscope   |    Keysigth DSOX3104T
• Scanner, low current and voltage measuerments   |    Keithley 7001
• High-voltage amplifier    |    TREK 2205
• Optical table    |     Newport RS 3000 (1.5 x 3.0 m)
• Probe station   |     Everbeing C-2
• Cryostats (multiple)    |     Oxford, Janis
• Luminescence spectrometer    |     Perkin-Elmer LS 50B
• Spectrometer, 200-850 nm      |     Ocean Optics USB2000
• Solar simulator   |    Oriel
• Laser, Ar+, 10 W MLVS, 1.3 W MLUV    |     Coherent innova 90C6
• Laser, Pulsed Nd:YAG, 6-8 ns, 1064 nm, 532 nm, 355 nm    |    Brilliant Ultra GRM, Quantel
• Laser, Dye    |    Coherent CR 599
• Laser, N2-dye pulse laser, 5 ns, 400 muJ/pulse   |    Oriel 79110
• Diode lasers (multiple), 785 nm, 45 mW    |    Power Technology PM(785-60), PMT(785-50)
• Diode laser, 905 nm, 8 mW    |     PMT(905-10)
• Diode lsaer, 980 nm, 40 mW   |    PMT(980-50)

Electrochemistry

• Potentiostat   |   IviumStat, CompactStat + 32 working electrode interface
• Potentiostat   |   IviumStat, Potentiostat/Galvanostat with EIS module
• Potentiostat   |   Gamry 620, Potentiostat/Galvanostat with EIS module
• Potentiostat   |   Autolab, PGSTAT 20 with EIS module
• Potentiostat   |   Autolab, PGSTAT 30 with EIS module
• Potentiostat   |   Autolab, PGSTAT 100
• 16-channel mV-meters (multiple)   |   Lawson Labs, EMF16 Interface

Surface chemical analysis instrumentation accessible via TopAnalytica

• TOF-SIMS   |   Time Of Flight Secondary Ion Mass Spectroscopy
• ESCA   |   Electron Spectroscopy for Chemical Analysis (XPS)
• SEM-EDS   |   Scanning Electron Microscopy with Energy Dispersive Spectrometer
• BIB   |   Broad Ion Beam cutting
• EPMA   |   Electron Probe MicroAnalysis (SEM-WDS)