CellCom and InFLAMES Proudly Presents the Seminar:

“CPS1: A Mitochondrial Urea Cycle Enzyme Moonlights as a Liver Injury Marker and Immune Modulator”

Warmly welcome to join us for an inspiring seminar with Prof. Bishr Omary. Omary is a Professor of Biomedical Science at Rutgers University in New Jersey, USA, and Senior Vice Chancellor for Academic Affairs and Research at Rutgers Health Campus. On May 23 he will become Honorary Doctor at Åbo Akademi University, Faculty of Science and Engineering.

Omary’s research focuses on rare diseases that cause damage to the liver, skin and other tissues. His work has led to seminal findings of molecular disease mechanisms, for example on the role and posttranslational regulation of intermediate filament keratins and lamins in gastrointestinal epithelia using disease models and in patients. His studies have led to several patents related to medical diagnostics and therapy.
Host: Diana Toivola (ÅAU Cell Biology, BioCity Turku CellCom Research Program and InFLAMES flagship; diana.toivola@abo.fi). Please contact Diana if you would like to book a meeting with Dr. Omary.

Coffee, with tea and buns are served at 12.30

Selected recent publications:

Kwan R, Chen L, Park MJ, Su Z, Weerasinghe SVW, Lee WM, Durkalski-Mauldin VL, Fontana RJ, Omary MB. The Role of Carbamoyl Phosphate Synthetase 1 as a Prognostic Biomarker in Patients With Acetaminophen-induced Acute Liver Failure. Clin Gastroenterol Hepatol. 2023, 21(12):3060-3069.e8. doi: 10.1016/j.cgh.2023.03.002.

Park MJ, D’Alecy LG, Anderson MA, Basrur V, Feng Y, Brady GF, Kim DI, Wu J, Nesvizhskii AI, Lahann J, Lukacs NW, Fontana RJ, Omary MB. Constitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injury. Proc Natl Acad Sci U S A. 2019, 116(18):9125-9134. doi: 10.1073/pnas.1822173116.

Kuo N, Li P, Cunha JB, Chen L, Shavit JA, Omary MB. The Histamine Pathway is a Target to Treat Hepatic Experimental Erythropoietic Protoporphyria. Cell Mol Gastroenterol Hepatol. 2025,19(6):101463. doi: 10.1016/j.jcmgh.2025.101463.